diff --git a/net-im/py-matrix-synapse/Makefile b/net-im/py-matrix-synapse/Makefile
index 124dc556428f..925cfed1d7f1 100644
--- a/net-im/py-matrix-synapse/Makefile
+++ b/net-im/py-matrix-synapse/Makefile
@@ -2,8 +2,7 @@
 
 PORTNAME=	matrix-synapse
 DISTVERSIONPREFIX=	v
-DISTVERSION=	1.49.2
-PORTREVISION=	2
+DISTVERSION=	1.50.1
 CATEGORIES=	net-im python
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
 
@@ -43,16 +42,16 @@ RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}jsonschema>=3.0.0:devel/py-jsonschema@${PY_F
 		${PYTHON_PKGNAMEPREFIX}typing-extensions>=3.7.4:devel/py-typing-extensions@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}ijson>=3.1:devel/py-ijson@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}pyjwt>=1.7.0:www/py-pyjwt@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}matrix-common>=1.0.0:devel/py-matrix-common@${PY_FLAVOR} \
 		${LOCALBASE}/share/certs/ca-root-nss.crt:security/ca_root_nss
 
 TEST_DEPENDS=	${PYTHON_PKGNAMEPREFIX}virtualenv>=15.0:devel/py-virtualenv@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}tox>=2.3.1:devel/py-tox@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}lxml>0:devel/py-lxml@${PY_FLAVOR} \
-		${PYTHON_PKGNAMEPREFIX}mock>=4.0.0:devel/py-mock@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}parameterized>=0.7.0:devel/py-parameterized@${PY_FLAVOR} \
 		${PYTHON_PKGNAMEPREFIX}authlib>=0.14.0:security/py-authlib@${PY_FLAVOR}
 
-USES=		python:3.6+
+USES=		python:3.7+
 USE_GITHUB=	yes
 GH_ACCOUNT=	matrix-org
 GH_PROJECT=	synapse
diff --git a/net-im/py-matrix-synapse/distinfo b/net-im/py-matrix-synapse/distinfo
index 296c3a13e3c7..8f98f7927e58 100644
--- a/net-im/py-matrix-synapse/distinfo
+++ b/net-im/py-matrix-synapse/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1640158042
-SHA256 (matrix-org-synapse-v1.49.2_GH0.tar.gz) = f5b0017e9d77db94fac853fbefbcb4538d879cb80f404b02003930c76f5cafab
-SIZE (matrix-org-synapse-v1.49.2_GH0.tar.gz) = 7637609
+TIMESTAMP = 1642580433
+SHA256 (matrix-org-synapse-v1.50.1_GH0.tar.gz) = cc35b442a4356cf85b2bc4d140d2de0d3b92bcc9176adc1526a46798b3569c86
+SIZE (matrix-org-synapse-v1.50.1_GH0.tar.gz) = 7654238