Created attachment 144813 [details] bug screeshot
notify maintainer note to submitter: always put the category in the title (e.g. mail/mimedefang) otherwise automatic assignment can never work.
To submitter: please check permissions to directory where it tries to create the socket. And second thing: it is not a good idea to post screenshots here. Next time consider copy and paste output from terminal.
ls -la /var/spool: drwxr-x--- 2 root mailnull 2 Jul 17 10:31 MIMEDefang
change permissions on mailnull:mailnull to directory /var/spool/mimedefang